Polycythemia Vera Treatment

Polycythemia Vera (PV) is a chronic illness and although it cannot be cured, it is frequently efficiently treated for a very long time. By reducing the number of excess blood cells, treatment aims to lessen the risk of thrombosis and alleviate symptoms. In India, a variety of treatments are used to cure Polycythemia Vera by bringing down hematocrit levels. For the hematocrit concentration to remain within normal ranges, careful medical management and therapy are crucial. When compared to other industrialized countries like the US, America, etc., the cost of a Polycythemia Vera treatment in India is much more affordable. The success is largely due to the skill of the hematologist and the oncologist as well as the state-of-the-art medical equipment used at the best hospitals in India.

What Is Polycythemia Vera?

An uncommon form of blood cancer called polycythemia vera (PV) occurs when your body makes an excessive amount of red blood cells. Your blood thickens and flows more slowly when you have an excessive amount of red blood cells. Within your blood arteries, the red blood cells have the potential to aggregate and form clots. PV can cause consequences that are life-threatening if it is not addressed. Your heart, brain, and other essential organs may receive less oxygen when your blood flows more slowly. A stroke or even death may result from a blood clot entirely blocking blood flow within a blood artery.

Leukemia, another kind of blood cancer, and myelofibrosis, a scarring of the bone marrow, are also long-term effects of PV. PV cannot be cured, however, medication can help you control your symptoms. In order to help avoid dangerous blood clots, your doctor may probably do routine blood tests and prescribe medication. If you have any symptoms of PV or are at risk for PV, it’s crucial to speak with your doctor.

What Causes Polycythemia Vera?

The soft, spongy substance in the middle of your bones, known as bone marrow, is where polycythemia vera develops. Here, fresh blood cells develop. A single gene in a single bone marrow stem cell defect causes PV. Most frequently, a gene known as JAK2 is to blame. The faulty gene instructs the stem cell to continue its own self-replication. All of the replicated cells keep procreating until the abnormal cells in your bone marrow outnumber the healthy ones. The JAK2 gene mutation is often acquired rather than inherited from a family member. It happens at some point in your life for unexplained reasons. However, there have been a few instances where polycythemia vera has affected several family members.

Polycythemia Vera Treatment Cost in India

Polycythemia Vera Treatment cost in India starts from INR 5,33,000 (6,400 USD). India offers healthcare at significantly lower costs as compared to other countries. Furthermore, the quality of the medical services and treatment provided there is on par with that of the best hospitals in the world and without accounting for travel, lodging, and food expenses.

Polycythemia Vera Treatment Cost in India might vary based on a variety of factors, including

• Depending on the hospital’s preferences, the cost of treatment packages may vary.
• The doctor’s knowledge and expertise in the area.
• The situation of the patient: The patient’s illness and whether additional treatment modalities are necessary for complete care.
• Hospitalization and travel time in the nation.
• Post-operative care is required.
• categorization of a hospital room.

What Are the Signs and Symptoms of Polycythemia Vera?

Polycythemia Vera develops gradually. For years, the illness may not show any symptoms at all. The thick blood that results from PV is the cause of the signs and symptoms when they appear. The blood’s ability to transport oxygen to every region of your body is slowed by its thickness. Numerous bodily components won’t function normally if you don’t have enough oxygen. PV symptoms and indications include:

• Dizziness, weakness, and headaches
• Breathing difficulties and shortness of breath while laying down
• A swollen spleen causes pressure or a feeling of fullness on the left side of the belly (an organ in the abdomen)
• Blind spots, double vision, and blurry eyesight
• Reddened face, itchiness all over (particularly after a warm bath), and a burning sensation on your skin (especially your hands and feet)
• Gum bleeding as well as copious bleeding from little incisions
• Loss of weight without cause
• Fatigue (tiredness) (tiredness)
• Excessive sweating
• Very painful swelling in a single joint, typically the big toe (called gouty arthritis)
• Rarely, those who have PV may experience bone discomfort.

What Are the Type of Diagnoses Done for Polycythemia Vera?

Your primary care physician could suggest that you see a hematologist if they suspect PV in you. A physician who focuses on identifying and treating blood-related illnesses and ailments is known as a hematologist. Blood tests may be used to identify PV in you. A complete blood count (CBC) is one of these tests, along with additional ones if necessary.

Complete Blood Count – A CBC is frequently the initial test done to identify PV. The CBC analyses several components of your blood. This test measures your levels of hemoglobin and hematocrit. Red blood cells need hemoglobin, an iron-rich protein, to transport oxygen from the lungs to the rest of the body. Your hematocrit determines how much space red blood cells take up in your blood. PV may be indicated by a high hematocrit or hemoglobin level. The CBC also measures the number of platelets, white blood cells, and red blood cells in your blood. Results that are abnormal might indicate PV, a blood problem, an infection, or another illness. People with PV may also have high white blood cell or platelet counts in addition to high red blood cell counts.

Other Blood Examinations –

• Blood smear: A little amount of blood is collected from a vein, often in your arm, for this test. A microscope is used to analyze the blood sample. You can tell whether you have an abnormally high level of red blood cells by looking at a blood sample. The test may also reveal aberrant blood cells connected to myelofibrosis and other PV-related disorders.
• Erythropoietin level: The amount of EPO in your blood is determined by this blood test. A hormone called EPO stimulates the production of fresh blood cells in your bone marrow. Low levels of EPO are found in those with PV. EPO levels in those with secondary polycythemia are frequently normal or high.

Tests for Bone Marrow – Your bone marrow’s health can be determined via bone marrow testing. These tests also reveal if your bone marrow is producing enough blood cells normally. Aspiration and biopsy are the two bone marrow examinations. Your doctor uses a needle to aspirate a little quantity of fluid bone marrow. Through a bigger needle, your doctor takes a tiny sample of bone marrow tissue for a biopsy. Following that, the samples are looked at under a microscope. It can be a clue that you have PV if the tests reveal that your bone marrow is producing an excessive amount of blood cells.

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